News Wire

Following disappointing phase 2b trial results with fispemifene in men with sexual dysfunction, California-based Apricus Biosciences has announced that it will suspend all clinical activities with the drug. Fispemifene is a once-daily orally administered selective estrogen receptor modulator (SERM)…
People with diabetes who rely on insulin have seen the cost of that drug triple in just a decade, according to a study from the University of Michigan. The increase in insulin costs was so large that, since 2010, the per-person spending on insulin has been higher than per-person spending on all other…
The FDA has given the green light to Descovy (emtricitabine 200 mg/tenofovir alafenamide 25 mg [F/TAF], Gilead Sciences), a fixed-dose combination for the treatment of human immunodeficiency virus-1 (HIV-1) infection. Descovy is indicated for use in combination with other antiretroviral agents in adults…
Staff reviewers at the FDA have supported the use of obeticholic acid (OCA, Intercept Pharmaceuticals) as monotherapy in patients with primary biliary cirrhosis (PBC) who did not respond to standard-of-care treatment. PBC results from autoimmune destruction of the bile ducts. The reviewers were unable…
Positive results have been reported from a phase 3 study investigating tofacitinib (Xeljanz, Pfizer) for the treatment of patients with psoriatic arthritis (PsA). The study evaluated the efficacy and safety of tofacitinib 5 mg and 10 mg twice daily (BID) in adults with active PsA who had shown an inadequate…
Patients receiving the investigational anti-inflammatory drug losmapimod (GlaxoSmithKline) for 12 weeks after a heart attack did not show improvements in the trial’s primary endpoint, the rate of cardiovascular death, subsequent heart attack, or urgent coronary revascularization, which includes placement…
The FDA has extended the action date for its review of the new drug application for an oral formulation of methylnaltrexone bromide (Relistor, Valeant Pharmaceuticals International) by three months to July 19, 2016. The FDA extended the date to allow a full review of new information submitted by Valeant…
New three-year data on Saxenda (liraglutide [rDNA origin] injection, Novo Nordisk), a glucagon-like peptide-1 (GLP-1) receptor agonist, have been presented at the Endocrine Society’s 98th Annual Meeting and Exposition, held in Boston, Massachusetts. The phase 3a SCALE (Satiety and Clinical Adiposity––Liraglutide…
Major drug companies implemented big price increases in the U.S.—in some cases more than doubling listed charges—for widely used medications during the past five years, according to an exclusive report from Reuters. Prices for four of the nation’s top 10 drugs increased more than 100% since 2011,…
More than 300 local, state, and federal government officials, health experts, and nongovernment partners gathered April 1 at the Centers for Disease Control and Prevention (CDC) to prepare for the likelihood of mosquito-borne transmission of the Zika virus in some parts of the continental United States.…
Statins may significantly reduce adverse cardiovascular events in people with average cholesterol and blood pressure (BP) levels who are considered to be at intermediate risk for cardiovascular disease, while the use of BP-lowering medications may be beneficial only in hypertensive patients, according…
An estimated one in 68 (14.6 per 1,000) school-aged children have been identified with autism spectrum disorder (ASD) in the United States, according to the Centers for Disease Control and Prevention (CDC). The agency’s surveillance summary, published in Morbidity and Mortality Weekly Report, shows…
The blood-testing devices that Theranos Inc. has touted as revolutionary often failed to meet the company’s own accuracy requirements for a range of tests, including one to help detect cancer, according to an article in the Wall Street Journal. The Journal got an early look at a federal report detailing…
The blood-testing devices that Theranos Inc. has touted as revolutionary often failed to meet the company’s own accuracy requirements for a range of tests, including one to help detect cancer, according to an article in the Wall Street Journal. The Journal got an early look at a federal report detailing…
A team led by Purdue University researchers is the first to determine the structure of the Zika virus. The findings provide insights critical to the development of effective antiviral treatments and vaccines, according to the investigators. Their report was published in Science. The team also identified…

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