News Wire

A data safety and monitoring board (DSMB) has determined that continuation of a phase 3 study of rindopepimut (Rintega, Celldex Therapeutics) in patients with newly diagnosed epidermal growth factor receptor vIII (EGFRvIII)-positive glioblastoma will not reach statistical significance for overall survival…
Patients with moderate-to-severe plaque psoriasis who did not respond to treatment with etanercept (Enbrel, Amgen) achieved significant improvement in their psoriasis plaques when treated with ixekizumab (Eli Lilly) in a phase 3 study. Results from the UNCOVER-2 trial were presented at the American…
New research indicates that another common mosquito may be able to carry the Zika virus, according to a Reuters report. The mosquito species Aedes aegypti is considered to be the main transmitter of Zika infections, but scientists in Brazil have announced that they were able to infect another species,…
The Centers for Disease Control and Prevention’s (CDC) latest Vital Signs report urges health care workers to use a combination of infection-control recommendations to better protect patients from health care-associated infections (HAIs). Many of the most serious antibiotic-resistant bacteria threaten…
Novo Nordisk has announced results from the LEADER trial, which investigated the cardiovascular safety of liraglutide (Victoza) during a period of up to five years in more than 9,000 adults with type-2 diabetes at high risk for major adverse cardiovascular events. The LEADER trial was an international,…
Marijuana use disorder is common in the U.S.; is often associated with other substance use disorders, behavioral problems, and disability; and goes largely untreated, according to a new study conducted by the National Institute on Alcohol Abuse and Alcoholism (NIAAA), part of the National Institutes…
The White House and the CDC will gather state and local officials next month to urgently craft a plan to attack the mosquito responsible for spreading the Zika virus, according to an exclusive report from Reuters. Federal health officials said they expect the first locally transmitted cases of Zika…
A study that compared preventable hospital admissions independently identified by physicians and the Prevention Quality Indicator (PQI) showed a level of agreement “no different than what would be expected by chance,” according to a report on the FierceHealthcare website. The PQI is a set of standardized…
Google’s engineers are working with the United Nations Children’s Emergency Fund (UNICEF) to analyze data in an effort to map and anticipate the spread of the Zika virus, according to a Reuters report. Google said in a statement that it was providing a $1 million grant to UNICEF to help the agency’s…
The FDA has approved a new indication expanding the use of fulvestrant (Faslodex, AstraZeneca) to include use in combination with palbociclib (Ibrance, Pfizer) in women with hormone receptor-positive (HR+), human epidermal growth factor receptor 2 negative (HER2–) advanced or metastatic breast cancer…
The FDA has informed Heron Therapeutics, Inc., that it expects to conclude its review of the new drug application (NDA) for granisetron (Sustol) injection, extended release, by early April 2016. In February, the FDA had announced that it would not meet the NDA’s Prescription Drug User Fee Act (PDUFA)…
A toxic protein called amyloid beta is thought to play a key role in the onset of Alzheimer’s disease (AD). In healthy people, amyloid beta is degraded by enzymes as it forms. However, in patients with AD, these enzymes appear unable to adequately perform their actions, causing the toxic protein to…
Even though reducing waste in health care is a top priority, analysts have missed the waste that can be created when expensive infused drugs are packaged containing quantities larger than the amount needed, according to a new study by researchers at the Memorial Sloan Kettering Cancer Center. The authors…
As an additional safety measure against the emerging Zika virus outbreak, the FDA has issued new guidance to reduce the potential risk of Zika virus transmission from human cells, tissues, and cellular and tissue-based products (HCT/Ps). The guidance addresses the donation of HCT/Ps from both living…
The FDA has given the nod to Odefsey (emtricitabine 200 mg/rilpivirine 25 mg/tenofovir alafenamide 25 mg) for the treatment of human immunodeficiency virus-1 (HIV-1) infection in certain patients. Emtricitabine and tenofovir alafenamide [TAF] are from Gilead Sciences, and rilpivirine is from Janssen…

Pages