Respiratory syncytial virus (RSV) bronchiolitis is a common and easily transmitted disease that affects infants, particularly premature infants, and young children, and is the leading cause of hospitalization among infants <1 year of age in the United States. RSV immunoprophylaxis tailored to local conditions can help ensure infant protection and avoid hospitalization. This Clinical Brief discusses the substantial variations in RSV seasonality throughout the country and the importance of using local RSV data to guide immunoprophylaxis management programs. A commentary is provided by Barry S. Lachman, MD, MPH, Medical Director, Parkland Community Health Plan, Dallas, Texas.
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