An international working group of 23 scientists convened by the International Agency for Research on Cancer (IARC), the cancer agency of the World Health Organization, has evaluated the carcinogenicity of drinking coffee, maté, and very hot beverages. The working group found no conclusive evidence for a carcinogenic effect of drinking coffee. However, the experts did find that drinking “very hot” beverages—defined as any beverage consumed at a temperature above 65° C—probably causes cancer of the esophagus in humans.
Maté is an infusion made from the dried leaves of Ilex paraguariensis that is consumed mainly in South America and to a lesser extent in the Middle East, Europe, and North America. It is traditionally drunk “very hot.” No conclusive evidence was found for drinking maté at temperatures that are not very hot.
“These results suggest that drinking very hot beverages is one probable cause of esophageal cancer and that it is the temperature, rather than the drinks themselves, that appears to be responsible,” says Christopher Wild, IARC Director.
A summary of the final evaluations was published June 15 in The Lancet Oncology, and the detailed assessments will be published as Volume 116 of the IARC Monographs.
Drinking very hot beverages was classified as probably carcinogenic to humans (Group 2A). This was based on limited evidence from epidemiological studies that showed positive associations between cancer of the esophagus and drinking very hot beverages. Studies in China, Iran, Turkey, and South America, where tea or maté is traditionally drunk very hot, found that the risk of esophageal cancer increased with the temperature at which the beverage was drunk. In experiments involving animals, there was also limited evidence for the carcinogenicity of very hot water.
“Smoking and alcohol drinking are major causes of esophageal cancer, particularly in many high-income countries,” stresses Dr. Wild. “However, the majority of esophageal cancers occur in parts of Asia, South America, and East Africa, where regularly drinking very hot beverages is common and where the reasons for the high incidence of this cancer are not as well understood.”
Esophageal cancer is the eighth most common cause of cancer worldwide and one of the main causes of cancer death, with approximately 400,000 deaths recorded in 2012 (5% of all cancer deaths). The proportion of esophageal cancer cases that may be linked to drinking very hot beverages is not known.
Cold maté did not have carcinogenic effects in experiments on animals or in epidemiological studies. Therefore, drinking maté at temperatures that are not very hot was not classifiable as to its carcinogenicity to humans (Group 3). This was based on inadequate evidence in humans for the carcinogenicity of drinking cold or warm mate and inadequate evidence in experimental animals for the carcinogenicity of cold maté as a drinking liquid.
Drinking coffee was not classifiable as to its carcinogenicity to humans (Group 3). The large body of evidence currently available led to the re-evaluation of the carcinogenicity of coffee drinking, previously classified as possibly carcinogenic to humans (Group 2B) by IARC in 1991.
After thoroughly reviewing more than 1,000 studies in humans and animals, the working group found that there was inadequate evidence for the carcinogenicity of coffee drinking overall. Many epidemiological studies showed that coffee drinking had no carcinogenic effects for cancers of the pancreas, female breast, and prostate, and reduced risks were seen for cancers of the liver and uterine endometrium. For more than 20 other cancers, the evidence was inconclusive.
Source: IARC; June 15, 2016.
Our most popular topics on Managedcaremag.com
Paul Lendner ist ein praktizierender Experte im Bereich Gesundheit, Medizin und Fitness. Er schreibt bereits seit über 5 Jahren für das Managed Care Mag. Mit seinen Artikeln, die einen einzigartigen Expertenstatus nachweisen, liefert er unseren Lesern nicht nur Mehrwert, sondern auch Hilfestellung bei ihren Problemen.