A provider network with adequate HIV experience is one key to preventing disruptions in services as this population makes the transition from social safety nets to commercial and Medicaid plans. The experience of health plans that have built strong HIV programs can be instructive.
David J. Brailer, MD, PhD
In 2004, President George W. Bush charged Brailer with putting everyone’s data on electronic health records. “No one then would have guessed how far we’ve come. We have seen very little partisan bickering, and I think that in part is why it has moved forward so well.”
Consumers commonly regard high price as an indication of high value whether they’re purchasing wine, automobiles, higher education or, alas, health care. Other nations have long used “quality-adjusted life-years” as a measure of value. Some oncologists think it should be used in the United States, as well.
Some experts argue that it encourages the use of costly unproven drugs. Instead of looking for genetic alterations serially, gene by gene, NGS relies on high speed parallel processing of a library of small DNA segments to “read” different types of alterations.
The Food and Drug Administration’s new “breakthrough drug” designation will almost certainly force P&T committees to review those products earlier than they might otherwise have.
First, half of active drugs trials involve some sort of biomarker. Second, biomarkers have re-invigorated research into treatments for diseases that have not changed in a long time. Third, old drugs or abandoned molecules might help people with specific molecular profiles.
Nonadherence to antihypertensive therapy is a substantial barrier to effective blood pressure (BP) control and has been associated with poor cardiovascular outcomes and increased medical costs. Patients prescribed single-pill combination therapies have higher rates of compliance and manage their BP better, researchers say.
Argument about safety reflects biosimilars and brands jockeying for market share
Edwin Webb, PharmD
Comprehensive medication management may improve outcomes in medical homes