2-dose varicella vaccination highly successful

Rates of chicken pox drop dramatically when patients receive two doses of the varicella vaccine, according to a study in the journal JAMA Pediatrics. Researchers looked at two locations: Antelope Valley, Calif., and West Philadelphia to see what happened when the two-dose regimen was introduced in 2006. Antelope Valley saw a 76% decline in varicella between 2006 and 2010; West Philadelphia saw a 67% drop.

“Declines in varicella incidence were seen across all age groups…. Varicella-related hospitalizations in the active surveillance areas declined nearly 50% during the first five years of the two-dose varicella vaccination program. With full implementation of the two-dose varicella vaccination program, it may be possible to eliminate the most severe outcomes of varicella.”

West Philadelphia, a Philadelphia neighborhood, had about 272,000 residents as of 2010; Antelope Valley had about 373,000. The data for West Philadelphia were gathered by the Philadelphia Department of Public Health’s Kids Immunization Database. In Antelope Valley, Kaiser Permanente Southern California gathered the data through its Kaiser Immunization Tracking System.

Varicella incidence after 2-dose vaccine

The solid line represents Antelope Valley, Calif. The dotted line is for a neighborhood in Philadelphia.

Source: “Impact of a Routine Two-Dose Varicella Vaccination Program on Varicella Epidemiology,” JAMA Pediatrics, Oct. 7, 2013


2014 Annual HEDIS® and Star Ratings Symposium Nashville, TN November 3–4, 2014
PCMH & Shared Savings ACO Leadership Summit Nashville, TN November 3–4, 2014
Medicare Risk Adjustment, Revenue Management, & Star Ratings Fort Lauderdale, FL November 12–14, 2014
World Orphan Drug Congress Europe 2014 Brussels, Belgium November 12–14, 2014
Healthcare Chief Medical Officer Forum Alexandria, VA November 13–14, 2014
Home Care Leadership Summit Atlanta, GA November 17–18, 2014
6th Semi-Annual Diagnostic Coverage and Reimbursement Conference Boston December 4–5, 2014
Customer Analytics & Engagement in Health Insurance Chicago December 4–5, 2014
Pharmaceutical and Biotech Clinical Quality Assurance Conference Alexandria, VA December 4–5, 2014
9th Semi-Annual Medical Device Coverage and Reimbursement Conference San Diego December 5, 2014
8th Annual Medical Device Clinical Trials Conference Chicago December 8–9, 2014
HealthIMPACT Southeast Tampa, FL January 23, 2015

Our other journal

P&T Journal for October 2014


The Clinical Trial Model Is Up for Review

Pyrazinamide-Induced Hyperuricemia

Lung Cancer Research Is Taking On New Challenges

Medical Applications for 3D Printing: Current and Projected Uses


Steady Progress on Parkinson’s Disease



Telling True Stories Is an ISMP Hallmark


FDA Accepts Its First Biosimilar Application

New Drugs/Drug News/New Medical Devices

Pharmaceutical Approval Update


Edoxaban: an Investigational Factor Xa Inhibitor