Original Research

Peer-viewed studies and review articles on managed care.

Original Research
Cost Effectiveness of the Insertion of Hydrogel Spacer in Men Treated With Radiation Therapy for Prostate Cancer
Elizabeth Brooks, PhD
Jim Hu, MD
James Yu, MD
Robert Bauserman, PhD
April Zambelli-Weiner, PhD
Matthew Yuen, PhD
Carter Little
ABSTRACT  Purpose: The study examined the cost effectiveness of prostate cancer radiotherapy with and without the use of a hydrogel spacer. Design and Methodology: Retrospective data from Truven Health Analytics’ Commercial Claims and Medicare Supplemental database between 2012 and 2017 identified…
Original Research
The COMPARE Study: Facility Costs Associated With Hysterectomy, Myomectomy, and the Sonata Procedure for Treatment of Uterine Fibroids
Elizabeth Brooks, PhD
Linda Mihalov, MD
Dipak Delvadia, DO
Saifuddin Mama, MD
Robert Bauserman, PhD
Gretchen E. Makai, MD
Matt Yuen, PhD
Carter Little
April Zambelli-Weiner, PhD
David J. Levine, MD
Abstract Purpose: The COMPARE study examined facility costs of sonography-guided transcervical fibroid ablation (TFA) using the Sonata System, hysterectomy, and myomectomy for the treatment of symptomatic uterine fibroids. Design and methodology: A facility-perspective cost analysis of hospital charge…
Original Research
A Financial Analysis of New York City Start-up Health Plans and Reasons for Their Losses
Adam E. Block, PhD
Starting a health plan is difficult and success is certainly not guaranteed. Of three 2014 start-up health plans in New York City, Health Republic closed in 2015 and CareConnect closed on New Year’s Eve 2017. Only Oscar remains, and it racked up cumulative losses of $235 million from 2014 to 2016.
Original Research
Real-World Analysis of Dispensed International Units of Coagulation Factor VIII and Resultant Expenditures for Hemophilia A Patients: A Comparison Between Standard Half-Life and Extended Half-Life Products
Amit Chhabra, MBBS, MPH
Patrick F. Fogarty, MD
Bartholomew J. Tortella, MD, MBA
Dean Spurden, PhD
José Alvir, DrPH
Margaret McDonald, PhD
Jennifer Hodge, PhD
Andreas M. Pleil, PhD
Real-world data challenge assumptions regarding typical factor usage and expenditures associated with product switching in patients with hemophilia A. There were higher expenditures over two years on hemophilia A patients using extended half-life (EHL) versus standard half-life (SHL) products.
Review Article
A Review of the Utility and Cost Effectiveness of Monitoring Fractional Exhaled Nitric Oxide (FeNO) in Asthma Management
Renée JG Arnold
Marc Massanari
Todd A. Lee
Elizabeth Brooks
Asthma is a common chronic respiratory disease affecting nearly 8% of the U.S. population. Fractional exhaled nitric oxide (FeNO) is a noninvasive biomarker for T2-driven (i.e., allergic) airway inflammation that could be used to improve diagnosis, optimize inhaled corticosteroid dosing, and monitor adherence.
Original Research
Cost-Effectiveness Analysis of Monitoring Fractional Exhaled Nitric Oxide (FeNO) in the Management of Asthma
Elizabeth A. Brooks, PhD
Marc Massanari, PharmD
Current asthma guidelines combine treatment, follow-up, and re-evaluation to manage asthma control, reduce impairment, and decrease risk of morbidity in patients. Analysis reveals that FeNO monitoring to guide asthma management is cost effective, increasing quality-adjusted life years while decreasing costs associated with asthma management.
Original Research
Economic Outcomes of a Precision Medicine Blood Test To Assess Obstructive Coronary Artery Disease: Results from the PRESET Registry
Joseph A. Ladapo, MD, PhD
Matthew J. Budoff, MD
Pejman Azarmina, MD, MSc
David Sharp, DO
Alice Baker, MPH
Bruce Maniet, DO
Lee Herman, MD
Mark Monane, MD, MS
An age/sex/gene expression score helped to identify patients with low current likelihood of obstructive coronary artery disease. These patients had lower costs of CAD care during one year of follow-up. Early reductions in cardiac referrals at 45 days among these patients persisted for one year.
Original Research
Assessing Provider Partnerships For Accountable Care Organizations
David Muhlestein, PhD, JD
Katelyn de Lisle
Thomas Merrill
ACOs need to provide comprehensive care management across a spectrum of provider specialties. To do this, they need a framework for evaluating potential partners that will help risk-bearing providers establish the partnerships that will enable them to achieve their goals.
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