News Wire

Positive results have been announced from ACHIEVE I (UBR-MD-01), the first of two pivotal phase 3 clinical trials evaluating the efficacy, safety, and tolerability of Allergan’s orally administered ubrogepant 50 mg and ubrogepant 100 mg compared with placebo in a single migraine attack in adults.…
The FDA has cleared the Embrace smart watch (Empatica, Inc.) for use by patients with epilepsy. Embrace uses advanced machine learning to monitor for the most dangerous kinds of seizures, known as “grand mal” or “generalized tonic-clonic” seizures, and sends an alert to summon caregivers’…
Positive results have been reported from a crucial immunotherapy trial that used a combination of two Bristol-Myers Squibb (BMS) drugs, nivolumab (Opdivo) and ipilimumab (Yervoy), to treat patients with a specific type of non–small-cell lung cancer patients. But previously undisclosed changes BMS…
Positive results have been announced from the phase 3 PROSPER trial in patients with nonmetastatic castration-resistant prostate cancer (CRPC). The results show that the use of enzalutamide (Xtandi, Astellas Pharma/Pfizer) plus androgen deprivation therapy (ADT) significantly reduced the risk of developing…
In theory, ACOs are groups of providers that band together to lower the cost of health while maintaining its quality by using various tools in the value-based care (aka population health) toolkit: care coordination, data analytics, avoidance of low-value services. But a study published in this month’s…
Hospitalizations blamed on the flu may be on track for a record in this increasingly challenging flu season, federal officials said Friday, and 16 more pediatric deaths were reported during the week.  “This is a very difficult season. The hospitalization rate is the highest we’ve seen,” said…
Updated results from a global clinical trial of the CAR T-cell therapy tisagenlecleucel (Kymriah, Novartis) show that children and young adults continued to show high rates of durable, complete remission of their high-risk form of acute lymphoblastic leukemia (ALL), according to a study published in…
Scientists in Japan and Australia have developed a blood test that can identify people who have high levels of a protein associated with Alzheimer's disease. If confirmed by further research, this long-sought test could help in the increasingly desperate search for therapies that halt the progression…
Once-weekly semaglutide (Ozempic, Novo Nordisk) led to greater reductions in HbA1c and body weight compared to dulaglutide (Trulicity, Eli Lilly) in the SUSTAIN 7 trial, according to results published in The Lancet Diabetes & Endocrinology. SUSTAIN 7 investigated the efficacy and safety of 0.5 mg semaglutide…
In an update on pharmaceutical pipeline projects tucked inside its financial results, FierceBiotech reports, Swiss drugmaker Roche announced that it was pulling the plug on several early- and late-stage candidates. The casualties: Lampalizumab (RG7417), a phase 3 drug that last fall failed two tests:…
The FDA is adding a boxed warning to obeticholic acid (Ocaliva, Intercept Pharmaceuticals, Inc.) in an effort to prevent incorrect dosing of the liver-disease medication in patients with moderate-to-severe primary biliary cholangitis (PBC). Obeticholic acid has been incorrectly dosed daily instead of…
Sarah Kliff at Vox had the best tweet about this morning’s announcement that Amazon, Berkshire Hathaway, and JPMorgan Chase were forming a new health care company. “Alexa, what is this new Amazon health care company?" https://t.co/oAAI0R4JQH — Sarah Kliff (@sarahkliff) January 30, 2018 The lack…
The National Institutes of Health (NIH) is teaming with government, biopharmaceutical, life science, and nonprofit organizations to overcome obstacles and increase success for advancing promising treatments for Parkinson’s disease (PD). Part of the NIH Accelerating Medicines Partnership (AMP), AMP…
A new study at Columbia University Irving Medical Center (CUIMC) challenges the popular notion that psychiatric medications are overprescribed in U.S. children and adolescents. When the researchers compared prescribing rates with prevalence rates for the most common psychiatric disorders in children,…
Amazon.com, Inc., Berkshire Hathaway, and JPMorgan Chase & Co. will form a health care company aimed at cutting costs for their U.S. employees, the three partners have announced. Reuters reports that the news sent shares in the broad health care sector sharply lower. The independent company will be…

Pages