Original Research

Peer-viewed studies and review articles on managed care.

Review Article
Asthma is a common chronic respiratory disease affecting nearly 8% of the U.S. population. Fractional exhaled nitric oxide (FeNO) is a noninvasive biomarker for T2-driven (i.e., allergic) airway inflammation that could be used to improve diagnosis, optimize inhaled corticosteroid dosing, and monitor adherence.
Original Research
Elizabeth A. Brooks, PhD
Marc Massanari, PharmD
Current asthma guidelines combine treatment, follow-up, and re-evaluation to manage asthma control, reduce impairment, and decrease risk of morbidity in patients. Analysis reveals that FeNO monitoring to guide asthma management is cost effective, increasing quality-adjusted life years while decreasing costs associated with asthma management.
Original Research
Joseph A. Ladapo, MD, PhD
Matthew J. Budoff, MD
Pejman Azarmina, MD, MSc
David Sharp, DO
Alice Baker, MPH
Bruce Maniet, DO
Lee Herman, MD
Mark Monane, MD, MS
An age/sex/gene expression score helped to identify patients with low current likelihood of obstructive coronary artery disease. These patients had lower costs of CAD care during one year of follow-up. Early reductions in cardiac referrals at 45 days among these patients persisted for one year.
Original Research
David Muhlestein, PhD, JD
Katelyn de Lisle
Thomas Merrill
ACOs need to provide comprehensive care management across a spectrum of provider specialties. To do this, they need a framework for evaluating potential partners that will help risk-bearing providers establish the partnerships that will enable them to achieve their goals.
Original Research
Douglas C. A. Taylor, MBA
Jessica L. Abel, MPH
Tim Bancroft, PhD
Paul Buzinec, MS
Alyssa Goolsby Hunter, MA
Robyn T. Carson, MPH
Carolyn Martin, MSW
As expected, pharmacy costs increased with the introduction of this new treatment in a market dominated by over-the-counter and generic treatments. On the other hand, outpatient GI-related and irritable bowel disease health care resource use and costs substantially decreased among commercial and Medicare patients following linaclotide treatment initiation.
Original Paper
Holly Miller, MD
Lucy Johns, MPH
The document “Feature and Function Recommendations To Optimize Clinician Usability of Direct Interoperability To Enhance Patient Care” offers recommendations from the clinician point of view. Widespread adoption of even a few of these recommendations by designers and vendors would greatly enhance care.
Original Research
Patrick Kearns, MD, FACP
Studies comparing team care of diabetes with traditional care should be redesigned, say researchers. “In order for redesign studies to support generalization of their findings, methodology should include a randomized, controlled study design with intention-to-treat analysis,” the study states.
Targeted Literature Review
Ray D. Page, DO, PhD
A. Christine Argento, MD
David B. Nash, MD, MBA
Alexandria Skoufalos, EdD
Eric S. Schaefer, MD
Accurate prognostic estimates can predict and document expected response to treatment, avoid ineffective and costly overtreatment, and facilitate meaningful discussions with lung cancer patients about the timing of best supportive care and hospice care when appropriate, thereby improving cancer care planning and quality scores.