Historically, health care professionals have focused on preventing influenza morbidity and mortality with vaccine, chiefly in the elderly and high-risk populations. Today, the larger public health objective is to prevent epidemics via complementary immunization strategies, which can include herd protection through vaccination of people who spread viruses to those at highest risk of complications and poor outcomes. New immunization strategies include vaccinating healthy children, adults, and health care workers. Efficacy data are presented for of trivalent inactivated influenza vaccine (TIV) and live attenuated influenza vaccine (LAIV), administered by nasal spray.
This supplement is based on the Influenza Vaccine Expert Roundtable, held in Chicago on April 19, 2007. The authors include Robert Belshe, MD, considered a leader in the field of influenza prevention.